IRCT2014120210617N2 IRCT 2015-01-15 Hamadan University of Medical Sciences Effect of Fennel on endometrial thickness Clinical Trial of the Effect of Fennel and Estrogen Compared with Estrogen Alone on Duration of Endometrial Thickness to Reach 8 millimeters in Women with Indication for Fetus Donation 2014-05-22 anticipated 100 Complete https://irct.ir/trial/11081 interventional Randomization: Randomized, Blinding: Not blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment. 2-3 female infertility. Intervention 1: Intervention group: patients will receive low dose tablet of oral contraceptive from the third day of menstrual cycle until the 21st day. Then from day 14 to 28 one ampule of gonadotropin releasing hormone (Buserelin) 0.5 milliliter will be administered subcutaneously daily. On the day 28 patients will receive oral tablets of estradiol valerate 6 milligrams/day and fennel as herbal tea, made with 10 grams of fennel boiled with 50 milliliter water for 20 minutes. On the 30th day and then every 3 days transvaginal ultrasound will be done to measure endometrial thickness. During this period 0.2 milliliter Buserelin will be continued subcutaneously. Intervention 2: Control group: patients will receive low dose tablet of oral contraceptive from the third day of menstrual cycle until the 21st day. Then from day 14 to 28 one ampule of gonadotropin releasing hormone (Buserelin) 0.5 milliliter will be administered subcutaneously daily. On the day 28 patients will receive oral tablets of estradiol valerate 6 milligrams/day (without fennel). On the 30th day and then every 3 days transvaginal ultrasound will be done to measure endometrial thickness. During this period 0.2 milliliter Buserelin will be continued subcutaneously.