IRCT2012090910508N1 IRCT 2012-10-16 Shahid Beheshti University of Medical Sciences Comparison of prophylactic efficacy of propranolol and pregabalin in headache control of children Comparison of prophylactic efficacy of propranolol and pregabalin in headache control of 3 - 15 years old children with migraine in Mofid children hospital 2011-03-21 anticipated 96 Complete https://irct.ir/trial/11009 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Not used, Assignment: Parallel, Purpose: Prevention. N/A Migraine. Intervention 1: We evaluate 96 children 3 to 15 years old coming to Mofid Children Hospital with complaint of headache who after history taking and examination the diagnosis established as migraine and hypersensitivity to anticonvulsants ruled out.Children randomly divided into two groups ( 1 and 2 ) .We treat children of group 1 with tablet of propranolol ( 10 to 20 miligram a day) used oral for at least 8 weeks and after 8 weeks since propranolol starting ,we compare the frequency , severity and period of headache in this group with group 2. Intervention 2: We evaluate 96 children 3 to 15 years old coming to Mofid Children Hospital with complaint of headache who after history taking and examination the diagnosis established as migraine and hypersensitivity to anticonvulsants ruled out.Children randomly divided into two groups ( 1 and 2 ) .We treat children of group 2 with capsule of pregabalin( 50 to 75 miligram a day ) used oral for at least 8 weeks and after 8 weeks since propranolol starting ,we compare the frequency , severity and period of headache in this group with group 1.