IRCT20090203001637N5 IRCT 2018-01-21 Vice-Deen for Research of Faculty of Basic of Medical Science of Tarbiat Modares University (TMU) Evaluation the relationship between cognitive function and inflammatory factors in patients with MS Evaluation of the relationship between BDNF, VEGF, proinflammatory and anti-inflammatory cytokines with cognitive function and quality of life following 6 weeks aerobic training in comparison with control group in relapsing-remitting multiple sclerosis patients. 2017-02-19 anticipated 20 Complete https://irct.ir/trial/1100 interventional Randomization: Randomized, Blinding: Single blinded, Placebo: Not used, Assignment: Parallel, Purpose: Supportive, Randomization description: Using random numbers table, Blinding description: The participant are blinded to type of intervention. The people who collect and analysis the blood samples from participants, are blinded. N/A Multiple Sclerosis. Intervention 1: Control group:They will take part in pre-post evaluation process only. They have be given medicine and diet similar to intervention group. they will not do and physical training in study period . Intervention 2: Intervention group :6 weeks endurance exercise with stationary bike with 70% maximal heart rate, 3 days in week. Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is Whenever it is effective for the treatment of these patients,it would be shared.