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IRCT2013070810190N4 IRCT 2013-07-17 Research deputy of Shiraz University of Medical Sciences Determination of the effect of broccoli sprouts on inflammation in patients with diabetes Determination of the effect of broccoli sprouts on pro- and anti- inflammatory markers in serum of patients with type 2 diabetes 2014-01-31 anticipated 40 Complete https://irct.ir/trial/10653 interventional Randomization: Randomized, Blinding: Single blinded, Placebo: Used, Assignment: Parallel, Purpose: Treatment. N/A Type 2 diabetes. Intervention 1: 10 g per day dried broccoli sprouts. Broccoli sprouts are an agricultural product cultivated by Agriculture Division in Shiraz University. Sprouts are consumed once per day for two months. Participants are asked to consume the sprouts with yogurt or other dishes. Intervention 2: 10 g/day corn starch colored with spinach powder. Participants are asked to consume the starch with yogurt or other dishes.
public Dr. Masoumeh Akhlaghi
Razi Blvd, College of Health and Nutrition
Shiraz Iran (Islamic Republic of) +98 71 1725 7288 akhlaghi_m@sums.ac.ir Shiraz University of Medical Sciences scientific Dr. Masoumeh Akhlaghi
Razi Blvd, College of Health and Nutrition
Shiraz Iran (Islamic Republic of) +98 71 1725 7288 akhlaghi_m@sums.ac.ir Shiraz University of Medical Sciences Iran (Islamic Republic of) Inclusion: Patients with type 2 diabetes with at least 3 years from the onset of the disease. Exclusion: Insulin therapy, taking especial medications such as hormones, hypoglycemic agents, and lipid lowering medications, vitamin and iron supplements, vitamin K antagonists, those with nephropathy, neuropathy, and cardiovascular disease, liver disease, cancers, autoimmune and inflammatory diseases, pregnant and lactating women, smokers, and those on especial diets, and those who make major changes in their diet during intervention. 30 years 65 years Both Treatment - Drugs Placebo 10 g per day dried broccoli sprouts. Broccoli sprouts are an agricultural product cultivated by Agriculture Division in Shiraz University. Sprouts are consumed once per day for two months. Participants are asked to consume the sprouts with yogurt or other dishes. 10 g/day corn starch colored with spinach powder. Participants are asked to consume the starch with yogurt or other dishes. C reactive protein. Timepoint: At the beginning of study and at the end of intervention. Method of measurement: Biochemical analysis. Tumor necrosis factor-alpha. Timepoint: At the beginning of study and at the end of intervention. Method of measurement: Biochemical analysis. Interleukin-6. Timepoint: At the beginning of study and at the end of intervention. Method of measurement: Biochemical analysis. Body mass index. Timepoint: At the beginning and at the end of study. Method of measurement: Weighing. Research deputy of Shiraz University of Medical Sciences Approved 2012-09-06 Shiraz University of Medical Sciences Zand Blvd Shiraz Iran (Islamic Republic of)