IRCT201205159766N1 IRCT 2012-07-14 Vice chancellor for research, Arak University of Medical Sciences Metoclopramide and serum therapy in control of vomiting in moderate dehydration due to Acute viral Gastroenteritis in children aged 1-7 years Metoclopramide and serum therapy in control of vomiting in moderate dehydration due to Acute viral Gastroenteritis in children aged 1-7 years 2009-03-21 anticipated 240 Complete https://irct.ir/trial/10304 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment. N/A acute viral gastroenteritis. Intervention 1: addition of Metocloperamid 0.1 mg/kg to serum therapy in case group. Intervention 2: standard serum therapy for isonatremic moderate dehydration as described by Nelson textbook of pediatrics in addition to electrolyte correction in control group as below : maintenance water is calculated as below for first 10 kg: 100 cc/kg for second 10 kg: 1000 cc + 50 cc/kg for over 20 kg: 1500 cc + 20 cc/kg 2400 cc maximum per day then we multiply that to the degree of dehydration( 5-10%) and so the water deficit is calculated. first we treat the child with 20 cc/kg of NSS in 20 minutes. total water needed( maintenance+deficit)minus the NSS first treated is the amount to treat with dextrose water 5% plus 20 mEq/L KCl . if ongoing loss happens, for each ml of diarrhea 1 ml of DW5%+ 20 mEq/L NaHCO3 + 20 mEq/L KCl and for each ml of Vomiting 1 ml of NSS+ 10 mEq/L KCl is administered per 1-6 hours as needed.